Excerpts - Chapter 3

WHY NOT JUST GET A TOTAL BODY SCAN?

In this high-tech age, there surely must be a better way to make medical diagnoses than pretending to be solving puzzles. High tech scans have arrived, and they must surely be able to pick up lurking infections in the body!

Total body scans miss many diagnoses….

Unfortunately, they don’t. There is no single test which will find all abnormal conditions in one’s body. In fact, total body scans are least likely to help diagnose a chronic low-grade smoldering infection in one’s system.

Nonetheless, high tech full-body scans are widely promoted these days to persons desiring more than the customary information about the state of their health. For some very good reasons, however, routine use of these scans is not endorsed by public health agencies such as the American Cancer Society, the American College of Radiology and the Food and Drug administration, and are usually not covered by insurance and Medicare. Patients often ask physicians whether they should pay out of pocket to have one of these scans.

The answer is not a simple yes-or-no. The issue is not whether such a scan might pick up unsuspected diagnoses, but rather, will it do so reliably? Those who are basically healthy without any symptoms or problems, generally expect reassurance from the scans that they are indeed completely healthy. If so, they won’t get what they are hoping for (take the case of our patient with shingles.) In the case of heart conditions, while certain of the scans are rather good at identifying coronary artery disease, one can walk away from a totally normal body scan or heart scan, and drop dead of cardiac arrhythmia (sudden death,) which the scan will not predict. A scan interpreted as normal can also overlook a leaky heart valve, which may require taking preventive antibiotics every time one has dental cleaning. One could also have a totally normal scan, yet have extremely high blood pressure, diabetes, AIDS or leukemia. In fact, the scans almost never pick up chronic infections such as syphilis, the hepatitis virus, stomach ulcer bacteria, early cancer of the cervix, a low-grade bladder infection or many other chronic smoldering infections.

Alternatively, some with certain symptoms hope that the scan will give a conclusive answer to a problem. They may be disappointed. A person experiencing severe pain in the neck and shoulders may be told that the scan shows a bone spur or a partially slipped disk. Yet the actual reason for their pain may not be the spur or the disk. Instead it may be an inflammatory muscle condition called polymyalgia rheumatica. All the scans in the world will miss this very important diagnosis with potentially serious consequences, unless the doctor orders one specific blood test (Erythrocyte Sedimentation Rate test - not usually included in routine blood testing – see also Section 6) to diagnose it.

Even though scans miss a multitude of important conditions, the proponents suggest that their importance may be in finding otherwise unsuspected cancer. Unfortunately, there, too, the test is wanting. Early cancer of the cervix won’t be identified by a scan, only by a Pap smear. Skin cancer such as melanoma won’t be discovered by the scan, only by inspection of the skin. Cancer of the blood, such as leukemia, won’t show up, only by blood test. Even small growths in the colon may not reliably be found by a scan, only by a sigmoidoscopic or colonoscopic examination. Furthermore, a normal scan today doesn’t guarantee that a person won’t have a newly formed cancer of the pancreas by next year. Even if one decides to have such a scan, it is unclear how often the scan should be repeated, at what age should one begin, and at what age the scans are no longer useful.

The need for detective work

If a total body scan doesn’t give a comprehensive answer about one’s health, then what will? As noted earlier, medical diagnosis is made by a trained diagnostician using a combination of information obtained from history of the patient’s symptoms, physical examination of the patient, followed by laboratory tests (which often but not always include x-rays, scans or other sophisticated tests,) synthesized into a final answer. No single part of this sequence of steps is reliable without putting all bits of the information together.

What if a scan does show something? X-rays are “shadow pictures” and do not prove whether a spot is cancerous or non-cancerous, infectious or non-infectious. A small spot found on the lung may be a scar left over from an old chest infection, and of little or no consequence. However, it could also be a very early cancer, or a lymph node harboring tuberculosis. The x-ray cannot conclusively tell which it is. There may not be any way to prove it except to biopsy or remove the questionable part of the lung. The concern of many physicians and public health agencies is that large numbers of scans indeed show such scars from old events or injuries, or show various other harmless cysts or malformations. As a result, substantial numbers of patients may be taken to surgery or for invasive biopsy only to be told that the finding noted on x-ray was of no health consequence.

Total body scans are not a substitute for thoughtful detective work. The scans will miss numerous important medical conditions including many infections and several types of cancer. They are only one tool in the diagnostic armamentarium of the master diagnostician. In order for routine use of such scans for screening purposes to be approved by responsible professional agencies, they have to provide not only interesting, but also proven useful information that will reliably benefit the person’s health. This must be demonstrated by so called outcome studies required by those professionals who believe in the need for evidence-based medicine.

There is nothing particularly wrong with these scans, though each exposes the patient to a significant dose of radiation. They give limited answers to limited questions. What role, if any, they should play in periodic checkups remains to be determined. Proponents point out that occasionally such scans uncover something truly important that no one has suspected. On occasion this is indeed true. However, it is not clear if this happened in the case of patients who had regular thorough checkups with a good diagnostician, or patients who went in for the test without having seen a doctor for years.

A total body scan could be done to rule out certain other possible problems, but most often won’t help you discover a hidden infection. To find answers to suspected medical problems, don’t place your hope in a single test, but seek a thorough and detailed evaluation. The diagnostician should select the best test to prove or disprove suspected conditions. There are some special tests and scans available that you have likely not heard of, that may be helpful in giving clues to hidden infections which I will outline later. Remember: one will only find what one is looking for.

E-Mail E.S. Daniel, M.D. Ph.D.